吴蓓丽

吴蓓丽，研究员，中科院上海药物所研究员、研究组组长，入选中科院百人计划，承担多项国家、科学院及地方的科研项目。

主要从事G蛋白偶联受体（GPCR）的结构生物学研究，研究工作集中在以下几个方面：1、GPCR高分辨率晶体结构解析；2、GPCR三维结构与功能关系的研究；3、基于GPCR结构的药物设计与研发。

2017年12月27日，被选举为上海市第十五届人民代表大会代表。 

2018年5月30日，吴蓓丽获陈嘉庚青年科学奖生命科学奖。 

Li P, Shu C, Wu B, Ding Y, Shen B and Rao Z. Crystallization and preliminary X-ray diffraction analysis of FKBP52 N-terminal domain. ActaCryst. D.

Li P, Wang L, Ding Y, Wu B, Shu C, Nie A, Li S, Shen B and Rao Z. Crystallization and preliminary X-ray diffraction analysis of FKBP12 complexed with a novel neurotrophic ligand. Protein and Peptide Letters

Wu B, Li P, Shu C, Shen B and Rao Z. Crystallization and preliminary crystallographic studies on the C-terminal Domain of human FKBP52. ActaCryst. D

Li P, Ding Y, Wu B, Shu C, Shen B and Rao Z. Crystal Structure of the N-terminal domain of human FKBP52. ActaCryst. D

Li P, Zhu J, Wu B, Gao F, Tien P, Rao Z and Gao GF. Crystallization and preliminary X-ray diffraction analysis of post-fusion six-helix bundle core structure from Newcastle disease virus F protein. ActaCryst. D

Li P, Wang L, Wu B, Shu C, Nie A, Shen B, Li S and Rao Z. Crystallization and preliminary X-ray diffraction analysis of FKBP12 complexed with a new neurotrophic ligand. Progress in Natural Science.

Wu B, Li P, Liu Y, Lou Z, Ding Y, Shu C, Ye S, Bartlam M, Shen B &Rao Z. 3D structure of human FK506-binding protein 52: implications for the Assembly of the glucocorticoid receptor/Hsp90/immunophilinheterocomplex. Proc Natl Acad Sci USA

Sun Y, Li X, Wu B, Sun P and Rao Z. Crystallization and Preliminary Crystallographic Analysis of Human eukaryotic translation initiation factor 5A （eIF-5A）。 Protein and Peptide Letters

Wu B, Liu Y, Zhao Q, Liao S, Zhang J, Bartlam M, Chen W &Rao Z. Crystal Structure of RS21-C6, involved in nucleoside triphosphate pyrophosphohydrolysis. Journal of Molecular Biology

Zhao Q, Oin L, Jiang F, Wu B, Yue W, Xu F, Rong Z, Yuan H, Xie X, Gao Y, Bai C, Bartlam M, Pei X &Rao Z. Structure of human Spindlin1: Tandem TUDOR-like domains for cell cycle regulation. Journal of Biological Chemistry.

Wu B, Chien EY, Mol CD, Fenalti G, Liu W, Katritch V, Abagyan R, Brooun A, Wells P, Bi FC, Hamel DJ, Kuhn P, Handel TM, Cherezov V & Stevens RC. Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists. Science.